PRP vs LLLT vs Hair Transplant

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Comparing PRP, LLLT, and Hair Transplant Results in London

Hair loss affects a significant proportion of men and women in the UK, particularly from androgenetic alopecia (AGA). In London, treatment options have expanded in recent years, ranging from non-invasive therapies to surgical solutions. Three frequently discussed methods are Platelet-Rich Plasma (PRP), Low-Level Laser Therapy (LLLT), and hair transplantation. Understanding their mechanisms, outcomes, and suitability is key to making an informed decision. Below, we compare these interventions based on current evidence and clinical practice.

Platelet-Rich Plasma (PRP) Therapy

PRP is an autologous treatment that involves collecting a small amount of your blood, isolating platelet-rich plasma through centrifugation, and re-injecting it into thinning areas of the scalp. The rationale is to exploit growth factors such as PDGF and VEGF to support follicular health and stimulate miniaturised hair.

Recent research supports PRP as a promising adjunct therapy in AGA. A controlled study demonstrated a significant increase in hair count and density after three monthly sessions of PRP in men with early-stage hair loss. Another 2021 analysis published in International Journal of Trichology confirmed that PRP significantly improved hair shaft calibre and hair density in both men and women after 12 weeks of treatment.

Costs in London typically range between £300 and £700 per session. A standard regimen includes three to four sessions spaced one month apart, with further maintenance treatments every 4–6 months to preserve gains. While PRP is not permanent, the low risk of complications and minimal downtime make it appealing, especially in early hair loss.

Low-Level Laser Therapy (LLLT)

LLLT is a non-surgical modality that delivers red light energy—usually between 630 and 670 nanometres—into the scalp to stimulate cellular activity within the hair follicle. The therapy is believed to enhance mitochondrial function, increase ATP production, and improve vascular supply to follicles.

Evidence remains mixed, but some trials do support its use. A 2020 double-blinded trial found that subjects using LLLT for 24 weeks saw a statistically significant increase in terminal hair count, especially in the vertex area. Another 2019 study observed improved scalp coverage in women with mild AGA after regular LLLT use.

London-based patients can opt for in-clinic treatment or home devices. Home-use caps and combs cost between £250 and £1,000, while clinic sessions may cost £50 to £150 per treatment. Three sessions per week are typical, with improvements seen from 3–6 months onward. LLLT’s effects are modest but may serve as a supportive treatment or maintenance option following PRP or surgery.

Hair Transplant Surgery (FUE)

Hair transplantation remains the most reliable and long-lasting solution for extensive hair loss. The Follicular Unit Extraction (FUE) method involves harvesting individual follicular units from the donor zone and reimplanting them in balding areas. This technique requires significant skill and is usually performed under local anaesthesia.

FUE produces predictable, long-term results in suitable candidates. A large retrospective study published in Plastic and Reconstructive Surgery Global Open (2021) followed over 1,000 patients and found that graft survival exceeded 90% when performed with optimal technique and postoperative care. Patients with stable donor areas and realistic expectations typically see dense, natural-looking outcomes after 9–12 months.

In London, hair transplant prices vary with the number of grafts. Smaller sessions (1,000 grafts) may start at £2,899 at My Hair UK, while larger cases involving 3,000 grafts can cost £4,499. Some clinics in central London may charge upwards of £10,000, depending on surgeon experience and demand. The upfront cost is higher, but results are permanent.

Clinical Comparison

PRP and LLLT are low-risk, non-surgical interventions that may help preserve existing hair and encourage regrowth. Both require continued treatment and are more effective in mild to moderate cases of AGA. Hair transplantation is better suited for patients with established baldness and sufficient donor supply. It offers by far the most comprehensive and long term results, but comes with surgical downtime and cost considerations.

From a clinical standpoint, combination therapy is becoming more common. PRP and LLLT are often used to support transplant outcomes, improving graft survival and maintaining surrounding hair.

GP Assessment Before Treatment

Before starting any hair loss treatment, it’s important to rule out reversible causes such as iron deficiency, thyroid dysfunction, or hormonal imbalances. Your GP can arrange a basic panel of blood tests to identify any underlying issues. If needed, they can refer you to a dermatologist or trichologist.

For patients in central London, reliable NHS GP practices include:

Bethnal Green Health Centre, 60 Florida St, London E2 6LL
Holborn Medical Centre, 64-66 Lamb's Conduit St, London WC1N 3NA
Gower Street Practice, 20 Gower St, London WC1E 6DP

Consulting your GP before visiting a specialist ensures a more tailored and appropriate treatment plan, especially if you are considering surgery or long-term therapies. Taking this step may save you time, cost, and unnecessary disappointment later.